![]() Inhaled steroids carry an increased risk of pneumonia. LAMA-containing inhalers appear to have an advantage over those without LAMA for preventing flare-ups.Ĭombination inhalers (LABA/LAMA and LABA/ICS), appear more effective for controlling symptoms than single-agent therapies (LAMA and LABA). The LABA/LAMA combination is likely the best treatment in preventing COPD flare-ups. We did not find a difference in benefits and harms, including side effects, among individual inhalers within the same treatment groups.The LABA/ICS combination had a higher incidence of severe pneumonia compared to the others.The LABA/LAMA combination was better than LABA/ICS combination, especially in people with a prior episode of flare-ups. ![]()
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